Utilizza questo identificativo per citare o creare un link a questo documento:
|Titolo:||Blood Lead, Manganese, and Aluminum Levels in a Regional Italian Cohort of ALS Patients: Does Aluminum Have an Influence?|
|Autori interni:||LAMBERTI, Monica|
MONSURRO', Maria Rosaria
|Data di pubblicazione:||2014|
|Rivista:||JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE|
|Abstract:||OBJECTIVES: To study aluminum (Al), manganese (Mn), and lead (Pb) influence on amyotrophic lateral sclerosis (ALS) development. METHODS: A total of 34 patients (10% of the regional ALS population) and 25 controls of an Italian region were enrolled. Metal concentrations were determined by atomic absorption spectroscopy. RESULTS: Serum Al concentrations in patients and controls were similar and lower than those provided by the Italian Society of Reference Values. No differences were observed in serum Mn concentrations, while, as expected, blood Pb levels were significantly higher in patients with ALS than those in controls. CONCLUSIONS: Results confirmed the association between high Pb blood levels and ALS; on the contrary, Al and Mn did not differ significantly in patients and controls, suggesting that Mn and especially Al may play a less important role in the ALS pathogenesis.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
File in questo prodotto:
Non ci sono file associati a questo prodotto.
- PubMed Central loading...
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.